Macrolide Chemistry
This includes: 6-O-methylation of Erythromycin thiocyanate to give Clarithromycin. Ring Expansion of to yield Azithromycin 9-N-O-proteinion of Erythromycin thiocyanate to yield Roxithromycin.
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Ketolides: |
Alembic Pharmaceuticals Limited has plans to introduce the 3 and/or 11-Oxo derivatives of Erythromycin A.
We have also manufactured the following derivatives through various chemistries: |
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Roxithromycin related Substances: |
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Erythromycin E Oxime-HCL |
N-demethyl Roxithromycin |
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Decladinosyl Roxithromycin |
Roxithromycin B |
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Roxithromycin - 10(z) |
Erythromycin 10-(E)-[O-[[(2-methoxyethoxy)methoxy]methyl]oxime] |
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Roxithromycin C |
2-O-[(2-methoxyethoxy)methyl erythromycin 10-(E)-[O-[[2-methoxy ethoxy)methoxy]methyl]oxime].
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Clarithromycin related substances: |
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Clarithromycin-9-Oxime |
15-nor-clarithromycin |
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N-demethyl Clarithromycin |
6-O-methyl Clarithromycin 9-O-methyl Oxime |
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6-11,di-O-methyl Clarithromycin |
N-demethyl-N-formyl clarithromycin |
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6-12,di-O-methyl Clarithromycin |
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Azithromycin Related Substances: |
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Erythromycin Iminoether |
Decladinosyl Azithromycin |
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Azaerythromycin |
N-methyl Azithromycin |
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Azaerythromycin B |
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